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Botanical illustration of Spiked Pepper
MedicinalSourced entry

Spiked Pepper

Piper aduncum

A tropical American pepper shrub, also called matico, whose leaves are traditionally used for stomach pain and indigestion. In mice, its leaf oil protected the stomach from ulcers.

Safety at a glance

  • PregnancyNothing recorded
  • BreastfeedingNothing recorded
  • MedicinesNothing recorded
  • Who should avoid itNothing recorded
  • AllergiesNothing recorded
  • ToxicityNothing recorded

Tap a box to read the safety notes below. “Nothing recorded” means our sources don't cover it, not that it's safe.

What is Spiked Pepper?

Plant family
Piperaceae, the pepper family
Parts used
The leaves
Where it grows
The tropical Americas
Genus
Piper
Species
aduncum

Regional names

Matico, Pimenta-de-Macaco, Aperta-Ruão

Traditionally used for

  • Stomach pain
  • Indigestion

Traditionally described as

  • Protects the stomach (in animal studies)

Natural compounds

What does the research say?

Traditional use

These are traditional uses, not proven treatments.

  • In traditional medicine, the leaves are commonly used to relieve stomach pain and digestive discomfort.[1]Study

Laboratory & animal research

Lab and animal results show what might be worth studying in people. They don't show that the herb has these effects in humans.

  • The leaf oil is mostly dillapiole. In mice, it protected the stomach lining from ulcers caused by alcohol or by the painkiller indomethacin, by up to about 91%.[1]Study

    Technical detail: 50–200 mg/kg orally; dillapiole 69.65%; involves nitric oxide synthase, sulfhydryl compounds and α2-adrenergic receptors.

In short

No studies in people or safety studies were found.

Sources

  1. [1] Gastroprotective action of Piper aduncum L. leaf essential oil mediated by α2-adrenergic biochemical pathways, nitric oxide synthase, and sulfhydryl compounds · DOI: 10.1016/j.jep.2026.121947Peer-reviewed study

This information is educational and traditional in nature, and is not a substitute for professional medical advice. Unfamiliar word? See what these words mean.