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Botanical illustration of Arcayuyo
MedicinalSourced entry

Arcayuyo

Dysphania graveolens

A strong-smelling relative of epazote, used in Mexico for stomach pain. It eased pain in mice, but its oil is poisonous and has killed a child.

Safety at a glance

  • PregnancyNothing recorded
  • BreastfeedingNothing recorded
  • MedicinesNothing recorded
  • Who should avoid itNothing recorded
  • AllergiesNothing recorded
  • Toxicity1 note →

Tap a box to read the safety notes below. “Nothing recorded” means our sources don't cover it, not that it's safe.

What is Arcayuyo?

Plant family
Amaranthaceae, the amaranth family
Parts used
The above-ground parts
Where it grows
Mexico and the southwestern United States to the Andes
Genus
Dysphania
Species
graveolens

Also called

Fetid Goosefoot

Regional names

Epazote de Zorrillo

Older scientific names

Chenopodium graveolens

Traditionally used for

  • Stomach pain

Traditionally described as

  • May relieve pain (in animal studies)
  • Poisonous oil

Natural compounds

Safety

Toxicity testing

  • The oil from this plant can kill. A girl under 3 died after a healer gave her 40 mL of it. She had vomiting, seizures, coma and brain swelling. The dose contained about 26 times the old medicinal dose of its toxic compound, ascaridole.[1]Study

What does the research say?

Traditional use

These are traditional uses, not proven treatments.

  • In Mexico, it's a traditional remedy for stomach pain.[2]Study

  • In the US Southwest, where it's called fetid goosefoot, the Zuni breathed the steam of the plant soaked in water for headaches, and the Western Keres used it to cause vomiting. The Hopi ground the seeds into corn meal dumplings.[3]Traditional text

Laboratory & animal research

Lab and animal results show what might be worth studying in people. They don't show that the herb has these effects in humans.

  • In mice, an extract, a tea and the oil from the plant reduced pain responses; the oil was strongest. Three of its compounds, pinostrobin, pinocembrin and chrysin, also eased pain.[2]Study

    Technical detail: 31–316 mg/kg orally; hot plate, writhing and formalin tests; effect reversed by naltrexone, flumazenil and bicuculline.

In short

Its oil contains ascaridole and can be fatal.

Sources

  1. [1] Fatal poisoning caused by oil of epazote, Chenopodium graveolensPeer-reviewed study
  2. [2] Antinociceptive pharmacological profile of Dysphania graveolens in mouse · DOI: 10.1016/j.biopha.2017.02.096Peer-reviewed study
  3. [3] Native American Ethnobotany Database: Chenopodium graveolens (fetid goosefoot) — Botanical Research Institute of Texas (BRIT); compiled by Daniel E. MoermanTraditional text

This information is educational and traditional in nature, and is not a substitute for professional medical advice. Unfamiliar word? See what these words mean.