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Botanical illustration of Sacred Thornapple
MedicinalSourced entry

Sacred Thornapple

Datura wrightii

A datura of the American Southwest. Its withanolides have been studied against cancer cells in the lab.

Safety at a glance

  • PregnancyNothing recorded
  • BreastfeedingNothing recorded
  • MedicinesNothing recorded
  • Who should avoid itNothing recorded
  • AllergiesNothing recorded
  • Toxicity1 note →

Tap a box to read the safety notes below. “Nothing recorded” means our sources don't cover it, not that it's safe.

What is Sacred Thornapple?

Plant family
Solanaceae, the nightshade family
Parts used
None recommended (the whole plant is poisonous)
Where it grows
The southwestern United States and northern Mexico
Genus
Datura
Species
wrightii

Also called

Sacred Datura

Traditionally used for

  • Lab research only

Traditionally described as

  • Contains withanolides and tropane alkaloids

Natural compounds

Safety

Toxicity testing

  • Datura species contain tropane alkaloids such as atropine and scopolamine, which cause poisoning with confusion, hallucinations, a fast heartbeat, seizures, coma and death. Sacred thornapple is a datura and shouldn't be eaten or drunk.[1]Study

What does the research say?

Laboratory & animal research

Lab and animal results show what might be worth studying in people. They don't show that the herb has these effects in humans.

  • Withanolides from the leaves and stems slowed the growth of brain, head and neck cancer cells in lab tests, but also of normal lung cells.[2]Study

In short

Datura species are poisonous and can cause hallucinations, seizures, coma and death.

Sources

  1. [1] Phytochemistry, Pharmacology, and Toxicology of Datura Species—A Review · DOI: 10.3390/antiox10081291Peer-reviewed study
  2. [2] Antiproliferative withanolides from Datura wrightii · DOI: 10.1021/np300766pPeer-reviewed study

This information is educational and traditional in nature, and is not a substitute for professional medical advice. Unfamiliar word? See what these words mean.