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Botanical illustration of Senna
MedicinalSourced entry

Senna

Senna alexandrina

A stimulant laxative from the leaves and pods, recognized in Europe for short-term relief of occasional constipation.

Safety at a glance

Tap a box to read the safety notes below. “Nothing recorded” means our sources don't cover it, not that it's safe.

Senna may interact with some medicines. If you take any medicine, read Interactions with medicines below and talk to your doctor or pharmacist before using it.

What is Senna?

Plant family
Fabaceae, the pea and bean family
Parts used
The leaves and pods
Genus
Senna
Species
alexandrina

Older scientific names

Cassia senna, Cassia angustifolia

Traditionally used for

  • Occasional constipation (short-term)

Traditionally described as

  • Stimulant laxative (anthraquinones)

Health topics

Where Senna appears in symptom search, and why. Being listed doesn't mean it's a proven treatment.

  • Constipation

    Recognized in Europe, based on scientific evidence, for short-term relief of occasional constipation, for no more than a week.

How it's prepared

Common ways Senna is prepared or sold. This isn't advice on how to take it; see Safety below.

Safety

Interactions with medicines

  • Talk to a doctor before using senna if you take heart medicines such as digoxin, medicines for heart rhythm or that affect the heart's QT interval, water pills, steroid medicines (corticosteroids) or licorice root. Long-term overuse can lower potassium, which strengthens the effect of digoxin and affects heart rhythm medicines.[1]Health agency

Who should avoid it

  • Don't use senna if you have:

    • A blocked or narrowed gut, or a gut that isn't moving
    • Appendicitis
    • Inflammatory bowel disease, such as Crohn's disease or ulcerative colitis
    • Stomach pain with no known cause
    • Severe dehydration

    It must not be used by children under 12.[1]Health agency

Side effects

  • Senna can cause stomach pain, cramps and watery stools, especially in people with irritable bowel syndrome or if the dose is too high. Long-term use can upset the body's water and salt balance and darken the lining of the bowel. It may turn urine yellow or red-brown, which is harmless. Allergic rashes and itching can occur.[1]Health agency

Pregnancy

  • Don't use senna during pregnancy, because lab data suggest some of its compounds (such as emodin) may damage genes.[1]Health agency

Breastfeeding

  • Don't use senna while breastfeeding: small amounts of its active compounds pass into breast milk.[1]Health agency

How much to use

  • Use senna for no more than 1 week; two or three times in that week is usually enough. Using stimulant laxatives for longer can damage how the bowel works and make you dependent on laxatives. If you need a laxative every day, see a doctor to find the cause.[1]Health agency

What does the research say?

Laboratory & animal research

Lab and animal results show what might be worth studying in people. They don't show that the herb has these effects in humans.

  • Senna contains anthraquinones, compounds that stimulate the bowel to move. They also change how the gut absorbs water and salt, so the stool holds more water and passes more easily.[2]Health agency

Research in people

  • Based on scientific evidence from at least 10 years of use in Europe, the European Medicines Agency recognizes senna leaf for short-term relief of occasional constipation in adults and teens over 12. It should only be used if changing your diet or taking a fiber laxative hasn't worked.[1]Health agency

  • In a 2021 trial of 90 adults with long-term constipation, mostly women, senna taken for 28 days improved symptoms in 69% of people, compared with 12% on a placebo. It worked about as well as magnesium oxide, another laxative, and improved quality of life.[3]Study

In short

Use for no more than a week. Not for pregnancy, breastfeeding or children under 12.

Sources

  1. [1] European Union herbal monograph on Senna alexandrina Mill. (Cassia senna L.; Cassia angustifolia Vahl), folium, Revision 1 — European Medicines Agency, Committee on Herbal Medicinal Products (HMPC)Government health agency
  2. [2] Senna leaf: summary for the public (EMA/697536/2018) — European Medicines Agency, Committee on Herbal Medicinal Products (HMPC)Government health agency
  3. [3] Senna Versus Magnesium Oxide for the Treatment of Chronic Constipation: A Randomized, Placebo-Controlled Trial · DOI: 10.14309/ajg.0000000000000942Peer-reviewed study

This information is educational and traditional in nature, and is not a substitute for professional medical advice. Unfamiliar word? See what these words mean.