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Botanical illustration of Lapacho
MedicinalSourced entry

Lapacho

Handroanthus impetiginosus

Also called pau d'arco, a South American tree whose inner bark is made into a tea and sold as a supplement for infections and cancer. Its benefits haven't been shown in people.

Safety at a glance

Tap a box to read the safety notes below. “Nothing recorded” means our sources don't cover it, not that it's safe.

Lapacho may interact with some medicines. If you take any medicine, read Interactions with medicines below and talk to your doctor or pharmacist before using it.

What is Lapacho?

Plant family
Bignoniaceae, the trumpet-creeper family
Parts used
The inner bark, usually made into a tea
Where it grows
South America
Genus
Handroanthus
Species
impetiginosus

Also called

Pau d'Arco, Taheebo, Trumpet Bush

Regional names

Ipê-Roxo

Older scientific names

Tabebuia impetiginosa, Tabebuia avellanedae

Traditionally used for

  • Infections
  • Cancer (as a supplement)

Traditionally described as

  • Antibacterial (in lab studies)
  • Antifungal (in lab studies)

Natural compounds

How it's prepared

Common ways Lapacho is prepared or sold. This isn't advice on how to take it; see Safety below.

Safety

Interactions with medicines

  • Don't take it with blood thinners such as warfarin, or antiplatelet medicines such as aspirin or clopidogrel. Its compound lapachol works in a similar way to warfarin and may raise the risk of bleeding.[1]General reference

Side effects

Pregnancy

  • In animal studies, lapachol harmed unborn young and caused anemia and chromosome damage.[1]General reference

What does the research say?

Traditional use

These are traditional uses, not proven treatments.

  • Tea made from the inner bark of South American lapacho trees is used in traditional medicine. Supplements are sold for infections and cancer.[1]General reference

Laboratory & animal research

Lab and animal results show what might be worth studying in people. They don't show that the herb has these effects in humans.

  • In lab studies, pau d'arco killed some bacteria, fungi and cancer cells, and may help reduce inflammation. These effects haven't been shown in people. Its compounds lapachol and beta-lapachone are thought to be responsible.[1]General reference

Research in people

  • Research in people is limited:

    • Small studies of a lapacho-based preparation suggested it may help prevent painful mouth sores in people having radiotherapy for head and neck cancer. The findings are preliminary.
    • A 1974 study found lapachol didn't help people with chronic myelocytic leukemia.
    • A small 2022 open-label study of adults with painful periods suggested it may reduce pain, but it had no comparison group.

In short

May raise the risk of bleeding, especially with blood thinners such as warfarin.

Sources

  1. [1] Pau D'arco — Memorial Sloan Kettering Cancer CenterGeneral reference

This information is educational and traditional in nature, and is not a substitute for professional medical advice. Unfamiliar word? See what these words mean.