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Botanical illustration of Aojiso
CulinarySourced entry

Aojiso

Perilla frutescens

Green shiso leaf, a Japanese herb and an official medicine in the Chinese and Japanese pharmacopoeias, used for colds, nausea and allergies. Perilla extracts eased hay fever in human studies.

Safety at a glance

  • PregnancyNothing recorded
  • BreastfeedingNothing recorded
  • MedicinesNothing recorded
  • Who should avoid itNothing recorded
  • AllergiesNothing recorded
  • ToxicityNothing recorded

Tap a box to read the safety notes below. “Nothing recorded” means our sources don't cover it, not that it's safe.

What is Aojiso?

Plant family
Lamiaceae, the mint family
Parts used
The leaves
Where it grows
East and South Asia
Genus
Perilla
Species
frutescens

Also called

Green Shiso, Shiso Leaf, Perilla Leaf

Traditional names

Perillae Folium

Traditionally used for

  • Food
  • Colds
  • Nausea
  • Hay fever

Traditionally described as

  • Leaves rich in rosmarinic acid

Health topics

Where Aojiso appears in symptom search, and why. Being listed doesn't mean it's a proven treatment.

  • Colds and Nasal Congestion

    A traditional remedy for colds, flu and a stuffy nose. Not tested for colds in people.

  • Hay Fever

    Perilla extracts helped allergic hay fever and itchy eyes in human studies, especially in young people.

  • Occasional Nausea

    Traditionally used for nausea and vomiting. Not studied in people.

Traditions that use it

Natural compounds

What does the research say?

Traditional use

These are traditional uses, not proven treatments.

  • Perilla leaf is an official herbal medicine in the Chinese and Japanese pharmacopoeias. Perilla has traditionally been used for coughs, colds and flu, fever, headache, a stuffy nose, nausea and vomiting, indigestion, allergies and anxiety.[1]Study

  • The leaves are eaten as a spicy vegetable and herb across East Asia. Leaves range from green to purple, and both colors can appear in the same variety.[1]Study

Laboratory & animal research

Lab and animal results show what might be worth studying in people. They don't show that the herb has these effects in humans.

  • Rosmarinic acid, a main compound in perilla, reduced allergic reactions in rats and mice about as well as a whole perilla decoction.[2]Study

Research in people

  • A 2023 review of human studies found perilla extracts helped allergic hay fever and itchy, watery eyes, especially in young people, and lowered blood fats. Most perilla research is in animals and cells, so more controlled trials are needed.[2]Study

In short

Perilla seeds can cause serious allergic reactions.

Sources

  1. [1] Ethnomedicinal, Phytochemical and Pharmacological Investigations of Perilla frutescens (L.) Britt. · DOI: 10.3390/molecules24010102Peer-reviewed study
  2. [2] Applications of Perilla frutescens Extracts in Clinical Practice · DOI: 10.3390/antiox12030727Peer-reviewed study

This information is educational and traditional in nature, and is not a substitute for professional medical advice. Unfamiliar word? See what these words mean.